Best Nootropic Supplements – Top Brain Boosting Smart Pills
Review top brain boosting smart pill nootropic supplements
Sponsored By Nootropic December 8, 2020

Reviewing the best nootropic supplements to buy out of all the top brain boosting cognitive enhancers that use safe smart pill ingredients to support mental health and peak performance is not easy to do without real research and eclectic efforts to sort through the overwhelming number of products available.
In fact, Nootropics have never been more popular.
Today, millions of people take cognitive enhancing supplements for brain power. Some take nootropic supplements for attention and focus. Others take nootropics for energy. Some take smart pills for overall health and wellness. Whatever nootropic effects you’re looking for, you can find them in nootropic brain supplements. However, there are more nootropics sold through Amazon and other major retailers than ever before. They all promise similar benefits, making it difficult to pick the right one for you. As nootropic experts, we want to help. Our editorial team ranked the best nootropic brain supplements available in 2020.Ranking the Best Nootropics
There are a number of crucial criteria these nootropic brands and smart drug companies must pass with flying colors to make the list of the best nootropics to buy this year. Ranking the top brain boosting cognitive enhancers is not easy, but the following guide will provide real clarity and insights into finding the right peak-performance formula for you. Based on our rankings, here are the best nootropic supplements of 2020:• Mind Lab Pro • SANE Vitaae • Nuzena Neuro Focus+ • Noobru Advantage • NaturalCell NeuroActiv6 • PureHealth Research Ageless Brain • Zenith Labs Brain C-13 • Organixx Ageless Brain • Brain Pill • NooCube Brain Productivity • Vitality Now Youthful Brain • Nootrogen • ProMind Complex • Synapse XT
Mind Lab Pro

SANE Vitaae
SANE makes a range of anti-aging supplements, and they make Vitaae specifically as an anti-aging nutritional supplement. The anti-aging clinical research formulation claims to target low energy, anxiety, depression, mood swings, brain fog, focus, metabolism, memory, and other brain-related symptoms. To target these benefits, Vitaae uses just 4 nootropic ingredients, including vitamin D (1,250% of your recommended Daily Value), 667mcg of folate (167% DV), 100mg of citicoline, and 50mg of CoQ10. The bulk of the formula consists of the VitaalMind Proprietary Blend, which has 1,800mg of acetyl-l-carnitine, L-carnitine tartrate, gymnema sylvestre leaf, extract, and omega-3 fatty acid concentrate. You take 3 capsules of Vitaae per day to support the advertised benefits. At $47 for a one-month supply, Vitaae is a reasonably-priced nootropic that uses proven doses of popular nootropic ingredients. SANE, like Opti-Nutra, is also a more reputable company than other nootropic makers. Price: $47 (30 Servings)Nuzena Neuro Focus+
Nuzena’s Neuro Focus+ is a nootropic supplement that claims to support memory recall, mental focus, cognitive function, and other benefits. Priced at just $30 for a one-month supply (30 servings), Nuzena Neuro Focus+ is like a multivitamin mixed with nootropic ingredients. You get a significant dose of vitamins A, C, D, E, B1, B2, B3, B6, and others, all of which are crucial for cognitive energy. You also get minerals like calcium, iron, magnesium, zinc, selenium, copper, and manganese, among others. What makes Neuro Focus+ different from an ordinary nootropic, of course, is its 692mg of a proprietary nootropic blend in each serving. That blend contains DMAE bitartrate, L-glutamine, glutamic acid, green tea extract, Bacopa monnieri extract, choline, and other ingredients. It’s difficult to determine the individual dose of these ingredients, but Neuro Focus+ is backed by strong reviews online, suggesting it should work as advertised to support cognition in various ways – and at a reasonable rate. Price: $30 (30 Servings)Noobru Advantage
Noobru is a unique nootropic compared to others on this list. The formula comes in a single-serve powder packet. You mix the powder with water or the beverage of your choice, then drink it daily to support cognitive benefits. Unlike some low-quality nootropics, Noobru is made by a reputable, UK-based company – not some shady ecommerce firm. Although the company hides most dosages within a proprietary formula, Noobru tends to have better reviews than other nootropics listed here. Key ingredients in Noobru include L-theanine, ashwagandha, vitamin B1, alpha GPC, vitamin B6, and phosphatidylserine, among others. Just pour it into water, shake it, then drink. At 47 GBP for 20 servings, it’s not the cheapest nootropic on this list – but it delivers quality where it counts. Price: £47.95 (20 Servings)ProMind Complex
ProMind Complex is one of the highest priced nootropic supplements listed here, but the feedback from this brain boosting formula online is rather superb. Although it doesn’t compete with similarly-priced supplements in terms of dosage in regards to some of its individual ingredients, the manufacturer makes big claims about the benefits and effectiveness of ProMind Complex through a compelling presentation that goes into the depths of how and why it was made to work at eliminating a toxic bacteria that causes memory loss. What ProMind Complex does have is a clever marketing campaign targeted to older adults seeking to capture their youthful cognitive energy. If you’re the type of person who wants to make their own high-powered nootropic stack at home, then ProMind Complex isn’t the right choice for you. If you’re willing to pay a premium price for someone to create your own nootropic based on science and research, then ProMind Complex could be an option as it does have a 60-day 100% money-back, empty-bottle guarantee. The ProMind Complex supplement ingredients are designed to first eradicate the bacteria, repair wounded brain cells and protect the entire brain and gums against plaque-forming bacteria. Price: $70 (30 Servings)Synapse XT
Synapse XT, like ProMind Complex above, is a higher-priced nootropic supplement with potent dosages that work a little differently than the other nootropic supplements. At $70 per bottle (plus shipping), you would expect Synapse XT to contain ultra-powerful doses of all active ingredients. Instead, the supplement contains a basic range of B vitamins and herbal extracts at surprisingly low dosages. However, the key differentiation here for the Synapse XT formula is hibiscus, along with Hawthorn Berry, Garlic, Rosemary, Magnesium and Potassium mixture that is nowhere else available on the planet today. Ultimately, Synapse XT is unlikely to have noticeable effects on cognitive energy or ability in comparison to the top nootropic pills listed here – especially compared to other high-priced options on this list. However, it’s backed by compelling marketing and is primarily targeted towards older adults who may be willing to pay a premium price for a pre-built nootropic stack. There is also the tinnitus relief and ringing the ears relief that may be a great start for those looking to just reach neutral again, before looking to add in the powerful boost nootropic supplements are notoriously known for all together. Price: $70 (30 Servings)NaturalCell NeuroActiv6

PureHealth Research Ageless Brain
Ageless Brain from PureHealth Research is a nootropic supplement priced at $50 per bottle, although you can drop the price to just $33 per bottle by ordering multiple bottles at once. Each serving of Ageless Brain contains caffeine, B vitamins, green tea extract, herbal extracts, and proven nootropics like Huperzine-A and Alpha-GPC, among other ingredients. By taking Ageless Brain daily, you can purportedly decrease anxiety and brain fog, improve memory and focus, boost memory, raise cognitive wellness, and enjoy other powerful benefits.Zenith Labs Brain C-13
Zenith Labs uses genuine doctors to formulate various nootropic supplements, including its popular Brain C-13 nootropic formula. Brain C-13 claims to provide advanced support for brain health, helping with your cognitive clarity and focus while supporting mental awareness, among other benefits. One thing we appreciate about Brain C-13 is that the supplement discloses the specific doses of all ingredients upfront. It doesn’t hide doses within a proprietary blend. That makes it easy to see exactly what you’re putting into your body with each serving. Key ingredients in Brain C-13 include Bacopa monnieri extract, turmeric root, ginkgo leaf, rosemary leaf, DMAE, and Huperzine A, among other ingredients. At $50 per bottle, it’s a mid-range price compared to other nootropics on our list. Price: $50 (30 Servings)Organixx Ageless Brain

Brain Pill

NooCube Brain Productivity
NooCube is a blend of nootropic ingredients that claim to support and enhance focus, mental speed, and memory, among other effects. By taking NooCube daily, you can safely and effectively improve cognition function using amino acids, vitamins, and other crucial ingredients. NooCube’s Brain Productivity formula achieves these benefits using Huperzine A, Alpha GPC, cat’s claw extract, Bacopa monnieri, and oat straw, among other ingredients. At $40 per bottle, NooCube is also much more reasonably-priced than many other options on this list, with further discounts available when ordering multiple bottles at once. Price: $40 (30 Servings)Vitality Now Youthful Brain
Vitality Now’s Youthful Brain is a nootropic supplement that uses B vitamins and herbal extracts to boost focus and concentration. The supplement, like many other supplements listed here, is specifically marketed towards older adults who want to “eliminate embarrassing senior moments,” explains the official website. Vitality Now’s Youthful Brain contains ingredients like Bacopa monnieri, phosphatidylserine, ginkgo biloba, and Huperzine A, among others. The supplement also contains a significant dose of vitamin B12 (1,000mcg or 16,667% of your Daily Value) in each serving, which should supercharge cognitive ability by boosting brain energy, although you can also get vitamin B12 from much cheaper sources. Overall, Youthful Brain doesn’t have the doses or ingredients to compete with the top-ranked nootropics on our list, but it should support various benefits as advertised, and it’s particularly popular among older adults and seniors. Price: $65 (30 Servings)Nootrogen
Nootrogen claims to be the “ultimate nootropic,” supporting cognition, energy, focus, and everyday stress, among other benefits. Nootrogen comes with sleek packaging and a flashy marketing campaign, although its ingredients are similar to other formulas listed here. The supplement contains a range of vitamins and minerals along with a 642mg proprietary nootropic blend. We don’t know the individual dosages within that proprietary blend, although we know the doses of most vitamins and minerals. Key ingredients in Nootrogen include DMAE bitartrate, L-glutamine HCL, glutamic acid, green tea extract, Bacopa monnieri extract, and others. Although doses seem comparable to other supplements listed here, Nootrogen is priced at just $30 per bottle, making it one of the best-value nootropics listed here. Price: $30 (30 Servings)How We Ranked
After much deliberation, our editorial team used the following factors to rank the best and worst nootropics above. Science-backed Ingredients: Even the most popular nootropic ingredients are backed by limited scientific evidence. We emphasized nootropics with effective doses of proven ingredients. We preferred ingredients backed by clinical trials in humans – not animals. The more evidence, the better. Clinical Trials: Most nootropic supplements have not gone through any clinical trials or studies. Most nootropics use ingredients that have gone through their own individual studies, but a rare few of the top-rated nootropics have completed their own clinical trials to verify their effectiveness. If a nootropic supplement has scientific evidence proving its specific formula is effective, we preferred that formula over competing options. Strong Dosages: Some nootropics contain the right ingredients at the wrong dosages. These nootropics might make big claims about their ingredients and their effectiveness, only to use a completely different dose than what was used in scientific studies. Although we didn’t want doses that were too powerful, we preferred nootropics with clinically-validated doses. Customer Reviews: Nootropics are largely subjective. It’s hard to measure ‘cognitive energy’ between individuals. Everyone’s brain works differently. You might feel brain fog for different reasons. That’s why customer reviews are particularly important for nootropic supplements. We considered customer reviews in our rankings, although we were wary of nootropics with large numbers of 5-star reviews and no 1-star reviews. Price & Value: Some people want to spend $30 on a one-month supply of a nootropic. Others want to spend over $100. We featured a range of nootropics for all budgets and needs, although we emphasized good value at every price point. Safety: Some nootropics contain dangerous levels of caffeine and other stimulants. Other nootropics contain doses that are proven to be safe. Advertised Benefits: Some nootropics claim to reverse the effects of aging, prevent Alzheimer’s, and provide other exaggerated benefits. They claim to make your brain feel 20 years younger, for example, or turn your memory into a steel trap. We appreciated manufacturers that were more transparent and honest with their marketing. Manufacturer Reputation & Transparency: Like any trendy supplement industry, nootropics are filled with low-quality companies seeking to make a quick buck. We appreciated nootropic manufacturers who were transparent about their background, manufacturing location, ingredient sources, and ingredient dosages, among other effects. Proprietary Formulas: Wherever possible, we tried to avoid proprietary formulas. However, they’re particularly common in the nootropic space, and many nootropic companies use proprietary formulas to hide individual dosages. We preferred supplements that listed individual ingredient dosages instead of packaging them into proprietary formulas. Valid Nootropic Ingredients: Technically, a multivitamin or cup of coffee could be considered a nootropic. Multivitamins contain B vitamins that are proven to support cognitive energy in various ways. Coffee contains caffeine, a stimulant many consider to be a nootropic. However, you can get coffee and multivitamins from anywhere. That’s why we preferred nootropic supplements with strong doses of Huperzine A, phosphatidylserine, citicoline, and other ingredients.Benefits of Nootropics
Nootropics are growing in popularity, and human research continues to catch up. While science has validated the benefits of some nootropics, other ingredients are backed by less scientific evidence. One of the biggest studies in the nootropic space was published in Human Psychopharmacology in 2016. This was one of the first studies to analyze a nootropic supplement as a whole instead of its individual ingredients. Researchers tested the effectiveness of Onnit Alpha Brain on 63 participants between ages 18 and 35. Participants received either Onnit Alpha Brain or a placebo over 6 weeks. At the end of the trial period, the Alpha Brain group “significantly improved verbal memory” and executive functioning compared to a placebo. Aside from that, few studies have examined nootropics as a whole. Most studies analyze individual ingredients within the formula. This 2001 study, for example, tested the effects of 300mg of Bacopa monnieri extract on participants over a 12 week period. Researchers observed that Bacopa monnieri “may improve higher order cognitive processes,” particularly with learning and memory. This 2008 study replicated that study and observed similar results, with researchers concluding that a 300mg dose of Bacopa monnieri extract “has potential for safely enhancing cognitive performance in the aging [population].” Other studies have reinforced the benefits of Bacopa monnieri. This study showed that Bacopa monnieri could boost information processing, reduce reaction times, and improve memory, among other benefits. Researchers have traced these effects to natural chemicals found in Bacopa monnieri extract called bacosides. The best extracts are rich with bacosides. As indicated in this study, Bacopa monnieri works best when used in doses of 300mg to 600mg. Many nootropic supplements above contain both ginkgo biloba and vinpocetine. Although you can find individual research validating both of these ingredients, some studies have analyzed the combination of the two ingredients. This 2001 study showed that ginkgo biloba and vinpocetine could support various cognitive benefits in healthy adults. Researchers gave adults a ginkgo biloba and vinpocetine supplement or a placebo for 14 days, then observed faster response times and better memory in the vinpocetine and ginkgo biloba group compared to a placebo. Some of the best nootropics above contain ashwagandha, which is arguably the longest-used nootropic available today. Ashwagandha has been used for centuries in Ayurvedic medicine to support stress and anxiety, among other benefits. Today, research shows ashwagandha can have genuine benefits on health and wellness, particularly in the brain. This 2016 review study analyzed dozens of studies on the herbal extract and concluded that ashwagandha has “nootropic potential” because of its ability to protect the mind against neurotoxins while enhancing memory, among other effects. Many nootropics use Huperzine A, a substance linked to improved memory and reaction time. In this 1999 study, researchers in Shanghai studied the effects of Huperzine A on participants and concluded that it could be a “promising agent” for cognitive impairment, memory decline, and even Alzheimer’s disease. L-theanine is one of the most popular nootropics available today. In fact, if you drink tea, you probably already get some L-theanine every day. L-theanine may nullify the unwanted side effects of caffeine, reducing jitters and anxiety associated with high doses of caffeine. One study found that taking 50mg of L-theanine, roughly the amount found in two cups of brewed tea, was associated with increased alpha brain wave activity, which could enhance creativity. Meanwhile, this study showed that L-theanine had complementary effects when paired with caffeine. L-theanine neutralized some of the unwanted side effects of caffeine without degrading its active effects. Rhodiola rosea is another popular herbal extract. Rhodiola rosea could help your body manage stress. This study showed that Rhodiola rosea could improve mood and decrease feelings of burnout, among other benefits. Panax ginseng is an herbal extract used for centuries in traditional Chinese medicine, Ayurvedic medicine, and other traditional fields of medicine. Studies show that 200 to 400mg of ginseng could reduce brain fatigue and improve brain performance, among other cognitive effects. Finally, this study on ginkgo biloba showed that taking the herbal extract daily could improve memory and brain processing in healthy adults over a 6 week period. Overall, many of the most popular nootropic ingredients have been extensively studied for their health and wellness benefits. Although few nootropics are backed by clinical trials, the individual ingredients within those nootropics are associated with various benefits in multiple studies.Side Effects of Nootropics
Healthy adults should not experience significant side effects when taking a normal dose of nootropics. However, if you are creating your own nootropic stack, then you could experience various side effects – especially if you’re messing around with high doses of nootropics. Fortunately, the supplements listed above use doses proven to be safe in multiple studies. When following the recommended serving sizes on your supplement, you should experience no significant side effects. Some of the common, mild side effects of nootropics include jitters, upset stomach, digestive issues, and other minor complaints. Overall, nootropics are well-tolerated by most people. You are more likely to experience nootropic supplement side effects if there is caffeine or other stimulants within your supplement. Some supplements contain a significantly higher dose of caffeine than the average cup of coffee, and it could increase jitters, anxiety, nausea, upset stomach, and other effects.Recommended Dosage of Nootropics
We recommend following the dosage on your nootropic supplement. Most supplements listed above recommended taking 1 to 2 capsules per day to support cognitive benefits. You should not exceed that dose, and you should talk to your doctor before taking any supplement – including a nootropic. That is especially true if you are taking medication or following any type of treatment plan. It does not matter what nootropic smart pill you opt to use, having the optimal dosage will yield the best results possible. Studies have shown certain nootropic ingredients work best at specific dosages. Ginseng seems to work best at doses of 200 to 400mg, for example, while Bacopa monnieri works best at doses of 300 to 600mg. There’s approximately 80 to 120mg of caffeine in the average cup of coffee. If you are sensitive to caffeine, check your nootropic supplement’s caffeine doses. Some supplements contain 200 to 500mg of caffeine.
FAQs About Nootropics
Q: What is a nootropic? A: A nootropic is a broad term for any drug, supplement, food, or beverage used to enhance cognitive ability. Q: How do I take a nootropic? A: Some nootropics come in the form of ordinary beverages – like green tea or coffee. Other nootropics come in the form of supplements – like the top-ranked supplements above. Some consider prescription-strength drugs like Ritalin as nootropics, while others claim only supplements are considered nootropics. Q: What’s the best nootropic? A: Any of the top-ranked nootropic supplements above are among the best nootropics in the industry. Q: What does the word ‘nootropic’ mean? A: The word ‘nootropic’ comes from two Greek words: noos for ‘intelligence’, vouc for ‘mind’, and trope for ‘turning’. The word ‘nootropic’ roughly translates to ‘mind/intelligence turning’. Q: Where does the word nootropic come from? Who first used the term nootropic? A: Nootropics have surged in popularity in recent years, although the word traces its history back 50 years. In the 1970s, a Romanian psychologist and chemist named Dr. Corneliu E. Giurgea combined Greek words together to create the term nootropic. Q: Are nootropics safe? A: When following the recommended serving size and taking nootropics from trusted brands, you should be perfectly safe when taking a nootropic. However, if you are creating your own stacks or experimenting with high doses, then nootropics can be dangerous or even lethal. Q: What’s in a nootropic supplement? A: Most nootropic supplements contain vitamins, minerals, herbal extracts, and plant extracts to support cognitive ability in various ways. Q: What are the benefits of a nootropic supplement? A: Nootropic supplement companies typically advertise benefits like improved memory and learning, better recall, better attention and focus, and improved cognitive energy, among other benefits. Q: Where do nootropics come from? A: The most reputable nootropic supplements available today are made in the United Kingdom, Canada, the United States, and other countries. Check your nootropic’s packaging to verify you have a high-quality formula made in a reputable facility. Q: Are nootropics legal? A: Yes, nootropic supplements are legal, and all supplements can only contain ingredients that are Generally Recognized as Safe (GRAS) to comply with FDA requirements. Q: Who should take nootropics? A: All types of people take nootropics. Students, athletes, parents, busy workers, people with competitive workplaces, traders, tradespeople, and others all take nootropics daily to support cognition in various ways. Q: Are professional athletes allowed to take nootropics? A: Most nootropic ingredients are not on the banned substances list in any professional organization, and athletes should be able to take a nootropic without issue. However, consider buying an NSF Certified for Sport nootropic to reduce the risk of cross-contamination or banned substances. Q: Are nootropics good for you? A: Nootropics aren’t good or bad for you, and supplements cannot advertise themselves as being ‘good’ for you. Some people can support various cognitive benefits with nootropics, while others experience no effects whatsoever. Q: Are nootropics proven to work? A: Nootropics have been shown to work in various studies in some people, although some people experience benefits by taking nootropics. Your experience may be different from someone else’s experience. Q: Are nootropics natural? A: Many nootropics advertise themselves as being ‘natural’ because they only contain plant-derived ingredients. However, check the label carefully to verify the use of natural or organic ingredients. Q: Are nootropics proven to work better than a placebo? A: Many nootropics have been shown to be more effective than placebos in various studies. However, some nootropics are backed by more research than others, so choose your nootropic carefully. Q: Are nootropics vegan? A: Most nootropic ingredients are naturally-derived from plant or synthetic sources, which means they’re vegan. However, some nootropic supplements come in a gelatin capsule. Gelatin is a pork or cow product, so gelatin nootropics are not vegan. Q: Can I get addicted to nootropics? A: Technically, you can get addicted to anything. Generally, nootropic supplements are not habit-forming, although those who experiment with higher doses of more advanced nootropics could experience various addiction-like effects. Q: Can I mix alcohol and nootropics? A: Alcohol and nootropics should not have negative interactions when used in moderate doses. However, the risk of negative interactions increases with higher doses of either alcohol or nootropics. Q: Do I need a prescription for nootropics? A: Although there are some prescription-strength nootropics that could be recommended by your doctor, all nootropic supplements are available to anyone without a prescription. Q: When’s the best time to take nootropics? A: You should take nootropics as directed on the supplement. Generally, most supplements are designed to be taken in the morning or at lunch to support cognitive wellness throughout the day. If taking your nootropic later in the day, you could have trouble sleeping (say, if the nootropic contains stimulants like caffeine).Final Word
Nootropic supplements are more popular than ever, and many people take nootropics daily to support a range of different benefits. Given all of the facts to review and findings to research, finding the best nootropic supplements and top brain boosting smart pills should be much easier now. The list of the most popular cognitive enhancers for peak brain function and healthy performance offer a wide range of high quality formulas worthy of consideration:• Best nootropic for everyone: Mind Lab Pro – buy here today • Best nootropic for memory: SANE Vitaae – buy here today • Best nootropic for focus: Nuzena Neuro Focus+ – buy here today • Best nootropic for drinks: Noobru Advantage – buy here today • Best nootropic for brain cell function: ProMind Complex – buy here today • Best nootropic for sound relief: Synapse XT – buy here today • Best nootropic for energy boost: NaturalCell NeuroActiv6 – buy here today • Best nootropic for mental clarity: PureHealth Research Ageless Brain – buy here today • Best nootropic for awareness and alertness: Zenith Labs Brain C-13 – buy here today • Best nootropic for more concentration: Organixx Ageless Brain – buy here today • Best nootropic for mood enhancement: Brain Pill – buy here today • Best nootropic for more productivity: NooCube Brain Supplement – buy here today • Best nootropic for more energy: Vitality Now Youthful Brain – buy here today • Best nootropic for a safe alternative: Nootrogen – buy here todayWith a detailed review of these nootropic supplements above, always know there is more to do to continually reach peak cognitive performance on a daily basis. It is amazing to see how many types of individuals can benefit from nootropics use. To test a nootropic supplement for yourself or enhance cognition, consider trying one of the top-ranked nootropics on the list above. They’re some of the best nootropics of 2021 available today.